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Here s a list of some of the mild side effects that Viagra can cause. To learn about other mild side effects, talk with your doctor or pharmacist, or read Viagra s prescribing information. Viagra; Descriptions. Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme In both the studies grapefruit led to an increase of peak concentration (Cmax) of sildenafil in plasma. One author showed that grapefruit juice increased the Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water and a molecular weight of 666.7. VIAGRA is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 25 mg, 50 mg, and 100 mg of sildenafil for oral administration. does grapefruit affect viagra In this study we investigated the influence of grapefruit juice, containing inhibitors of intestinal CYP3A4, on the pharmacokinetics of sildenafil and N -desmethylsildenafil. Methods: In a randomized crossover study, 24 healthy white male volunteers received single 50-mg doses of sildenafil.

‘Viagra, which is used for treating erectile dysfunction, when combined with grapefruit juice can reach toxic levels that result in men having hot flushes. It can also significantly lower their Grapefruit juice increases sildenafil bioavailability and tends to delay sildenafil absorption. Sildenafil pharmacokinetics may become less predictable with grapefruit juice. Although One author showed that grapefruit juice increased the mean oral bioavailability of sildenafil by 23%. Concluding, the important growth in grapefruit juice consumption should be carefully